- Five related cases of flea-borne typhus in Pico-Union, all hospitalized, have been investigated by LA County Public Health.
- County officials report a record 220 cases in 2025, surpassing the previous record of 187 in 2024.
- Nine out of 10 diagnosed patients in 2025 required hospitalization, highlighting the disease's severity.
- Cases have steadily increased since 2010, affecting residents aged 1 to 85.
On July 29, 2026, the Los Angeles County Department of Public Health issued a warning due to a localized outbreak of flea-borne typhus in the Pico-Union neighborhood after identifying five related cases this year, all requiring hospitalization. While all patients have recovered, the outbreak coincides with a record number of countywide cases, prompting urgent prevention warnings.
Localized Outbreak in Pico-Union
Health officials confirmed five cases in the Pico-Union area, all linked by exposure to fleas carrying Rickettsia typhi bacteria. The patients, who ranged in age from one to 85, were hospitalized but have since recovered. This cluster is part of a broader surge: Los Angeles County reported 220 flea-borne typhus cases in 2025, the highest on record. In addition to this cluster, health officials reported three other localized outbreaks in Central Los Angeles, Santa Monica, and Willowbrook during 2025.
Record High Cases and Hospitalization Rate
According to Public Health data, nine out of 10 people diagnosed with flea-borne typhus in 2025 required hospitalization. The previous record of 187 cases was set in 2024. The illness has been rising steadily since 2010, with infected fleas commonly found on rats, free-roaming cats, and opossums in the county. In 2018 and 2019, the county recorded 109 and 92 cases, respectively, before numbers surged in recent years. In Long Beach, 34 cases were reported between January and mid-October 2025, marking a record year for that city. The issue became a political flashpoint in 2018-2019, prompting city officials to consider removing carpets from City Hall and the LAPD to deploy a germ-fighting robot at Central Station after an officer contracted typhus. That came after the department was fined by state officials for failing to train employees about typhus transmission. Of particular concern were homeless encampments and areas with accumulated trash, which attract rats.
Symptoms and Treatment
Symptoms typically appear one to two weeks after a flea bite and include fever, headache, rash, body aches, chills, nausea, vomiting, and muscle pain. Officials urge anyone with these symptoms—especially after possible exposure to fleas or animals—to seek prompt medical care. The disease is treatable with antibiotics if caught early.
Prevention Tips for Residents
To reduce risk, health officials recommend using veterinarian-approved flea control year-round, keeping pets indoors, and applying EPA-registered insect repellents outdoors. Residents should avoid feeding stray animals, secure trash cans, and seal crawl spaces to deter rodents and wildlife. Contact local animal control if stray animals or opossums are frequent. "As flea-borne typhus cases continue to increase across Los Angeles County, preventing exposure to infected fleas is more important than ever," said LA County Health Officer Dr. Muntu Davis. "Community members can help protect themselves and their neighbors by keeping pets on flea control year-round, avoiding stray animals, and making sure wildlife cannot live in or around their homes."
Local California Context
This outbreak is centered in Los Angeles County's Pico-Union neighborhood, a densely populated area. The county's warm climate and urban wildlife create conditions for flea-borne disease transmission. Officials emphasize that flea-borne typhus is not spread from person to person, making flea control the primary defense.
Background
Flea-borne typhus has been on the rise in Los Angeles County since at least 2010, with cases increasing from under 20 annually to over 200 in 2025. The disease is endemic in local animal populations, and urbanization has brought people into closer contact with carriers like opossums and feral cats. The recent political attention in 2018-2019 highlighted the challenges of controlling the disease in urban settings with homeless encampments and stray animals.
Conclusion
As cases reach unprecedented levels, Los Angeles County residents are urged to take proactive steps to prevent flea exposure. Early diagnosis and treatment are critical, but preventing bites remains the most effective strategy. Stay informed through the LA County Department of Public Health.